Animation of Phagocytosis by Enhanced Attachment (Opsonization)

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Enhanced attachment is the attachment of microbes to phagocytes by way of molecules such as the antibody molecule IgG or proteins produced during the complement pathwayscalled C3b and C4b. Following attachment, polymerization and then depolymerization of actin filaments send pseudopods out to engulf the microbe and place it in a vesicle called a phagosome. Following acidification of the phagosome, lysosomes containing digestive enzymes and microbicidal chemicals fuse with the phagosome containing the ingested microbe and the microbe is destroyed.

Flash animation illustrating Phagocytosis by Enhanced Attachment (Opsonization).swf by Gary E. Kaiser, Ph.D.
Professor of Microbiology, The Community College of Baltimore County, Catonsville Campus
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Last updated: October, 2018
Please send comments and inquiries to Dr. Gary Kaiser