Transport of Substances Across a Membrane by Uniporters

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Uniporters are transport proteins that transport a substance across a membrane down a concentration gradient from an area of greater concentration to lesser concentration. The transport is powered by the potential energy of a concentration gradient and does not require metabolic energy. Interaction between the substrate and the uniporter causes a conformational change in the uniporter enabling the substrate to cross the membrane. Amino acids, nucleosides, sugars, and other small molecules are often transported across membranes by uniporters.

Flash animation of transport of a substance across a membrane by a uniporter.swf by Gary E. Kaiser, Ph.D.
Professor of Microbiology, The Community College of Baltimore County, Catonsville Campus
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Last updated: Feb., 2018
Please send comments and inquiries to Dr. Gary Kaiser