Transfer of Conjugative Plasmids and Multiple Antibiotic Resistance in Bacteria
Via R Plasmids

R plasmids are conjugative plasmids coding for mating pair formation and also multiple antibiotic resistance. A conjugative plasmid is self-transmissible, in that it possesses all the necessary genes for that plasmid to transmit itself to another bacterium by conjugation. Conjugation genes known as tra genes enable the bacterium to form a mating pair with another organism, while oriT (origin of transfer) genes determine where on the plasmid DNA transfer is initiated. The plasmid also possess genes coding for resistance to a number of different antibiotics.

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