Objectives for "Using Antibiotics and Chemical Agents to Control of Bacteria"
B. Ways in which our Control Agents Affect Bacteria
After completing this section you should be able to perform the following objectives.
1**. Describe 6 different ways antibiotics or disinfectants may affect bacterial structures or macromolecules and state how each ultimately causes harm to the cell.
2*. State which of the following groups of antibiotics: 1) inhibit peptidoglycan synthesis; 2) inhibit nucleic acid synthesis; 3) alter bacterial 30S ribosomal subunits blocking translation; or 4) alter bacterial 50S ribosomal subunits blocking translation.
a. macrolides (erythromycin, azithromycin, clarithromycin, dirithromycin, troleandomycin, etc.), oxazolidinones (linezolid), and streptogramins
b. penicillins, monobactams, carbapenems, cephalosporins, and vancomycin
c. fluoroquinolones (norfloxacin, lomefloxacin, fleroxacin, ciprofloxacin, enoxacin, trovafloxacin, etc.), sulfonamides and trimethoprim, and metronidazole
d. aminoglycosides (streptomycin, neomycin, netilmicin, tobramycin, gentamicin, amikacin, etc.) and tetracyclines (tetracycline, doxycycline, demeclocycline, minocycline, etc.)
3. State two modes of action for disinfectants, antiseptics, and sanitizers.
(*) = Common theme throughout the course
(**) = More depth and common theme
Gary E. Kaiser, Ph.D.
Professor of Microbiology
The Community College of Baltimore County, Catonsville Campus
This work is licensed under a Creative Commons Attribution 4.0 International License.
Based on a work at http://faculty.ccbcmd.edu/~gkaiser/index.html.
Last updated: September, 2018
Please send comments and inquiries to Dr. Gary Kaiser