Mode of Action of Oxazolidinones Blocking the Attachment of the 50S Ribosomal Subunit to the Initiation Complex

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The oxazolidinones (linezolid) bind to the 23S rRNA in the 50S ribosomal subunit and interfere with the formation of the initiation complex.

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by Gary E. Kaiser, Ph.D.,
Professor of Microbiology, The Community College of Baltimore County, Catonsville Campus
This work is licensed under a Creative Commons Attribution 4.0 International License.
Based on a work at http://faculty.ccbcmd.edu/~gkaiser/index.html.

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Last updated: September, 2018
Please send comments and inquiries to Dr. Gary Kaiser