Binding of LPS and Chemokines to Neutrophils Triggering Extracellular Killing

The binding of LPS released from the gram-negative cell wall binds to toll-like receptor- 4 (TLR- 4), as well as the binding of chemokines such as interleukin-8 (IL-8) to their respective chemokine receptors on the surface of neutrophils stimulates the neutrophils to release proteases and toxic oxygen radicals for extracellular killing.

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