BIOL 230
MICROBIOLOGY
LECTURE E-TEXT
UNIT 4

MICROBIOLOGY LEARNING OBJECTS

UNIT 4

I. THE INNATE IMMUNE SYSTEM

II. ANTIGENS

I. THE INNATE IMMUNE SYSTEM

A. The Innate Immune System: An Overview

B. Cells Involved in Body Defense

1. Defense Cells in the Blood: The Leukocytes

2. Defense Cells in the Tissue: Dendritic Cells, Macrophages, and Mast Cells

C. Immediate Innate Immunity

1. Antimicrobial enzymes and Antimicrobial Peptides

2. The Complement System

a. The Classical Complement Pathway

b. The Lectin Pathway

c. The Alternative Complement Pathway

3. Anatomical Barriers to Infection, Mechanical Removal of Microbes, and Bacterial Antagonism by Normal Flora Bacteria

D. Early Induced Innate Immunity

1. Pathogen-Associated Molecular Patterns (PAMPs) and Damage-Associated Molecular Patterns (DAMPs)

2. Pattern-Recognition Receptors (PRRs)

3. Cytokines Important in Innate Immunity

4. Harmful Effects Associated with Abnormal Pattern-Recognition Receptor Responses and/or Cytokine Production

5. Phagocytosis

a. An Overview of Phagocytic Defense

b. The Process of Phagocytosis

6. Natural Killer Cells (NK Cells) and Invariant Natural Killer T-Lymphocytes (iNKT Cells)

7. Inflammation

8. Nutritional Immunity

9. Fever

10. The Acute Phase Response

11. Intraepithelial T-lymphocytes and B-1 cells


II. ANTIGENS