An allosteric enzyme has both an active site for its substrate and an allosteric site for an inhibitor of the enzyme. In the absence of enzyme's inhibitor, the substrate is able to bind to the enzyme's active site and end products are produced. If the inhibitor is present, it will bind to the enzyme's allosteric site. This, in turn, alters the enzyme's active site so it can no longer bind its substrate and no end products are produced.
Flash animation illustrating Non-competitive Inhibition
with Allosteric Enzymes
in the Absence of an Inhibitor.swf by Gary E. Kaiser, Ph.D.
Professor of Microbiology, The Community College of Baltimore County, Catonsville Campus
This work is licensed under a Creative Commons Attribution 4.0 International License.
Based on a work at http://faculty.ccbcmd.edu/~gkaiser/index.html.
Last updated:November, 2018
Please send comments and inquiries to Dr. Gary Kaiser