Opsonization of a Virus

The Fab portion of IgG binds to epitopes of the viral surface. The Fc portion can now attach the virus to Fc receptors on phagocytes for enhanced attachment. Once attached to the phagocyte by way of IgG, the virus can be engulfed more efficiently, placed in a phagosome, and destroyed by lysosomes. C3b and C4b from the activated complement pathways are also able to attach viruses to phagocytes.

Doc Kaiser's Microbiology Home Page
Copyright © Gary E. Kaiser
All Rights Reserved
Updated: April, 2009
Please send comments and inquiries to Dr. Gary Kaiser