Fig. 6: Formation of the Membrane Attack Complex (MAC) during the Complement Pathways

Multiple molecules of C9 combine with C5b,C6, C7, and C8 to form the Membrane Attack Complex (MAC). C5b6789n, functions as a Membrane Attack Complex (MAC). This helps to destroy Gram-negative bacteria as well as human cells displaying foreign antigens (virus-infected cells, tumor cells, etc.) by causing their lysis. It can also damage the envelope of enveloped viruses.


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