Formation of the Membrane Attack Complex (MAC) and Cell Lysis

This C5b6789n, or membrane attack complex (MAC), puts pores into lipid bilayer membranes of human cells to which antibodies have bound. This results in cell lysis. MAC can also damage the envelope of enveloped viruses and put pores in the outer membrane and cytoplasmic membrane of gram-negative bacteria causing their lysis.


Doc Kaiser's Microbiology Home Page
Copyright © Gary E. Kaiser
All Rights Reserved
Updated: April 18, 2007
Please send comments and inquiries to Dr. Gary Kaiser