Enhanced Attachment (Opsonization) of a Bacterium By Way Of the Antibody IgG


The Fab portion of IgG binds to epitopes of a microbe. The Fc portion can now attach the microbe to Fc receptors on phagocytes for enhanced attachment, also known as opsonization. Once attached to the phagocyte by way of IgG, the microbe can be engulfed more efficiently and placed in a phagosome, and destroyed by lysosomes.


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