Cytotoxic T-Lymphocyte (CTL)-Induced Apoptosis of a Virus-Infected Cell

Killing of the infected cell or tumor cell by apoptosis involves a variety of mechanisms:

This animations shows destruction of both the cytoskeleton and nucleoprotein of the infected cell. As the infected cell breaks up into apoptotic fragments, the fragments are subsequently removed by phagocytes. This reduces inflammation and also prevents the release of viruses that have assembled within the infected cell and their spread into uninfected cells.

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