Scanning Electron Micrograph of a Cytotoxic Lymphocyte Destroying a Tumor Cell:
CTL Attaching to a Tumor Cell

The CTL is the cell on the right. The T-cell receptor/CD8 molecules on CTLs recognize corresponding peptides bound to MHC-I molecules on the tumor cell. After binding, the CTL secretes perforins and granzymes to put pores in the membrane of the tumor cell and trigger apoptosis.

Cytotoxic Lymphocyte Destroying a Tumor Cell. © John Ding-E Young, Chau-Ching Lin, and Gilla Kaplan, authors.
Licensed for use, ASM MicrobeLibrary.


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