Self Quiz for The Adaptive Immune System: Cell-Mediated Immunity: Activating Antigen-Specific Cytotoxic T-Lymphocytes (CTLs)

Study the material in this section and then write out the answers to these questions.
Do not just click on the answers and write them out. This will not test your understanding of this tutorial.

 

1. The role of cytotoxic T-lymphocytes (CTLs) in body defense.

a. State from what cells cytotoxic T-lymphocytes are derived. (ans)

b. Describe how they can react with and destroy virus-infected cells, cells containing intracellular bacteria, and cancer cells without harming normal cells. (Indicate the role of following: TCR, CD4, MHC-I, and peptides from endogenous antigens.) (ans)

c. State the mechanism by which cytotoxic T-lymphocytes kill the cells to which they bind. (Indicate the role of the following: perforins, granzymes, caspases, and macrophages in the process.) (ans)

2. Multiple Choice (ans)



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