BIOL 230 Lecture Guide - Suppression of the Synthesis of MHC-I Molecules

Fig. 7C: Suppression of the Synthesis of MHC-I Molecules

Numerous viruses, such as the cytomegalovirus (CMV) and adenoviruses can block the formation of MHC-I molecules by the infected cell. As a result, no viral peptide is displayed on the infected cell and the CTLs are no longer able to recognize that the cell is infected and kill it.