Fig. 7D: Blockage of the Binding of Peptide Epitopes from Viruses to MHC-I Molecules

Epstein-Barr virus (EBV) down regulates several host proteins involved in attaching viral epitopes to MHC-I molecules and displaying them on the surface of the host cell. As a result, no viral peptide is displayed on the infected cell and the CTLs are no longer able to recognize that the cell is infected and kill it.

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