Learning Objectives for "The Adaptive Immune System: Antibodies - The 5 Classes of Human Antibodies"

After completing this section you should be able to perform the following objectives.


1. State which classes (isotypes) of human antibodies possess the following characteristics:

a. are monomers
b. is a pentamer
c. is a dimer
d. activates the classical complement pathway by its Fc portion
e. binds to macrophages and neutrophils by its Fc portion
f. binds to NK cells by its Fc portion
g. crosses the placenta
h. functions as a B-cell receptor
i. the first antibody produced during an adaptive immune response
j. binds to components of mucous by its Fc portion
k. found mainly in body secretions
l. binds to mast cells and basophils by its Fc portion and promotes inflammation, coughing, sneezing, vomiting, and allergic reactions
m. binds to eosinophils by its Fc portion and promotes the removal of parasitic worms and arthropods

2. Match the antibody isotype with its description.

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