Fig. 6: Sticking of Phagocytes to Larger Cells by Opsonization, Step-1

The Fab portions of IgG or molecules of C3b bind to epitopes on human cells recognized as foreign, such as virus-infected cells, tumor cells, or cells involved in autoimmune reactions. This enables phagocytes to attach to the cell by way of their Fc and C3b receptors.

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