Fig. 7: Anamnestic Response

After the primary exposure to an antigen, there is an inductive period of generally several days to a week when no measurable antibodies are detected in the serum. This is the period when the antigen is being exposed to immunocompetent cells, being processed by APCs, clonal selection and clonal expansion are taking place, and B-lymphocytes are differentiating into plasma cells and B-memory cells. Because of the memory cells, however, a second exposure to the same antigen results in more antibodies being made faster for a longer period of time

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Sept. 29, 2003

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