Fig. 9: Activation of a B-lymphocyte through the Cross Linking of B-Cell Receptors by TI-2 Antigens

TI-2 antigens, such as capsular polysaccharides, are molecules with multiple, repeating subunits. These repeating subunits activate B-lymphocytes by simultaneously cross-linking a number of B-cell receptors. This cross-linking activates chemical signals that lead to transcription of antibody and cytokine genes.

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