Fig. 3: An iNKT-Lymphocyte Being Activated by Interleukin-12 Produced by a
PAMP/PRR- Activated Dendritic Cell

1. Microbial pathogen-associated molecular patterns (PAMPs) bind to their corresponding pattern-recognition receptors (PRRs) on antigen-presenting dendritic cells.
2. The PAMP/PRR interaction activates the dendritic cell enabling it to synthesize and secrete the cytokine Interleukin-12 (IL-12).
3. IL-12 binds to IL-12 receptors on the surface of iNKT cells and activates these cells.


Illustration of An iNKT-Lymphocyte Being Activated by Interleukin-12 Produced by a PAMP/PRR- Activated Dendritic Cells .jpg by Gary E. Kaiser, Ph.D.
Professor of Microbiology, The Community College of Baltimore County, Catonsville Campus
This work is licensed under a Creative Commons Attribution 4.0 International License.
Based on a work at http://faculty.ccbcmd.edu/~gkaiser/index.html.

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Last updated: August, 2019
Please send comments and inquiries to Dr. Gary Kaiser